To summarize the nursing experience of a patient with huge space occupying of cardiac non-Hodgkin lymphoma. The key points of nursing include：monitoring and volume management of circulatory system,predictive nursing of percutaneous ventricular septal biopsy,nursing of individual chemotherapy complications,rehabilitation guidance during acute heart failure in bed,risk management of cross-hospital transport,and individual psychological nursing. After careful multidisciplinary treatment and nursing care,the patient was getting better;the heart tumor was smaller than before;the cardiac function increased from level Ⅳ to Ⅱ;no chest tightness,shortness of breath and discomfort were reported after walking on the ground for 30 min.

This article summarizes a series of emergency management strategies such as early warning activation,continuous advancement,and scientific prevention and control in the centralized treatment of coronavirus disease 2019（COVID-19） from the perspective of nursing service department. The strategies include fully functioning the longitudinal command and horizontal coordination of the nursing service department,reasonable allocating treatment and nursing human resources,and efficiently promoting in-hospital fever clinics,isolation wards,ICU and other centralized treatment and referral and treatment of provincial critical illness patients. 5 prevention and control groups were established for training and examination,management and supervision,psychological assistance,logistical support,and reporting and publicity,so as to ensure the sustainability of prevention and control. With the support of National Clinical Medical Research Center of Infectious Diseases,we optimize the work process,improve the nursing specifications,solve clinical problems,and lead the provincial nursing work. The implementation of these strategies ensures the timely,orderly,safe and efficient centralized treatment. The goal of zero death for severe cases and zero infections for medical staff has been achieved.